Vertebral bone destruction in sickle cell disease: infection, infarction or both.

نویسندگان

  • A Kooy
  • L J de Heide
  • A J ten Tije
  • A H Mulder
  • H L Tanghe
  • J A Kluytmans
  • J J Michiels
چکیده

Infectious and vaso-occlusive vertebral bone and joint destruction in two patients with sickle cell disease (SCD) are featured by H-shaped vertebrae, kyphotic angulation, osteolysis of endplates and collapse of intervertebral discs as shown by X-ray films and magnetic resonance imaging. Staphylococcal serology supported the diagnosis of staphylococcal osteomyelitis/spondylo-discitis in both SCD patients. The difficulties of establishing the causes and treatment of the osteoarthropathy in these particular cases are discussed in the light of the literature.

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عنوان ژورنال:
  • The Netherlands journal of medicine

دوره 48 6  شماره 

صفحات  -

تاریخ انتشار 1996